Human LDL Receptor Protein (Fc Tag) 10231-H05H from Sino Biological, Inc.

Product Specs
ItemHuman LDL Receptor Protein (Fc Tag)
CompanySino Biological, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number10231-H05H
Quantity100µg
Conjugate/TagC-mouse IgG1-Fc
FormatLyophilized from sterile 50 mM Tris, 100 mM Glycine, 10 mM NaCl, pH 8.0
Purity> 85 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human LDLR consists of 1001 amino acids and predicts a molecular mass of 111.2 kDa
SpeciesHuman
Molecule NameLDLR
Source/Expression SystemHEK293 Cells
NCBI Full Gene Namelow density lipoprotein receptor
NCBI Gene AliasesFH, FHC, FHCL1, LDLCQ2
Activity1.Loaded Recombinant Human LDLR/LDL Receptor Protein, mFc Tag (Cat. No. 10231-H05H) on ProA Biosensor, can bind Recombinant Human PCSK9 (D374Y) Protein, His Tag (Cat. No. 29698-H08H1) with an affinity constant of 2.57nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Loaded Recombinant Human LDLR/LDL Receptor Protein, mFc Tag (Cat. No. 10231-H05H) on ProA Biosensor, can bind Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein, His Tag (Cat. No. 10594-H08H1) with an affinity constant of 3.08nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Loaded Recombinant Human LDLR/LDL Receptor Protein, mFc Tag (Cat. No. 10231-H05H) on ProA Biosensor, can bind Recombinant Human PCSK9 Protein, His Tag (Cat. No. 29698-H08H) with an affinity constant of 16nM as determined in BLI assay (Sartorius Octet RED384) (QC tested)